Based on the MEMS Nanopump™ technology, the JewelPUMP™ offers unmet improvement in diabetes therapy. It was designed with the help and assistance of diabetic patients, nurses and endocrinologists with the objective of bringing a significant contribution to patient's Quality of Life. Conceived as a patch pump without tubing, it gives more flexibility and freedom to the patient. Its extremely small size and weight allows wearing it completely hidden under the clothes, its ultra-precision permits an accurate delivery of insulin even at very low delivery rates and independently of external conditions, its built-in functional monitoring guarantees perfect safety during its use and its general conception makes it more affordable for patients.
Debiotech'’s JewelPUMP™ is made of two parts: one re-usable part (that contains the electronics with a large display, vibration alarm, buzzer and programming capabilities, as well as remote communication for distant programmation and control) and one disposable part (with the reservoir and the pumping mechanism, as well as batteries) for almost one week treatment. Reservoir filling is done only once for 6 days and small air bubbles don't need to be evacuated as they are retained in the reservoir by a new type of filter. Once both parts are assembled together, the entirely waterproof unit is attached to the skin with an adhesive patch that contains an auto-inserted infusion cannula with no tubing which can be changed every 3 days. The unit can be removed and reattached at will to the existing adhesive patch, or to a new one at another location, enabling more freedom for the patient. We also have another version of the re-usable electronic part which includes bolus buttons directly on the pump, for a self administration in the event the remote is not immediately available.
The JewelPUMP™ comes with an insulin reservoir capacity of 4.5ml (450 U), representing a total volume in use of 22 cc and a total weight of 0.78oz (22g, incl. battery). With such a small size (approx. 60x40x13mm), it can be hidden under the clothes and makes the disease almost invisible. Size is often perceived as a major issue for patients: pumps are heavy and cumbersome. The JewelPUMP™ is up to four times smaller than today's conventional pumps, or about half the volume of existing patch pumps, while containing over two times the amount of insulin on board, and therefore represents a clear progress in patients’ daily life.
The MEMS technology used in the JewelPUMP™ allows a very tight control and
precision of the pumping mechanism. Each pump actuation delivers only 200
nanoliters of drug (0.02 U), and reproducibility is better than 5%, bringing
it very close to physiological delivery of insulin. This precise control may
also extend the use of pumps for children who have low need of insulin and
where injection must be especially well controlled. On the longer run, we are
also working here in
Safety is guaranteed by several features: closed fluidic path at rest, anti-free-flow system, permanent functional monitoring and immediate occlusion detection. In addition to the safety features present on current insulin pumps, the JewelPUMP™ is preventing air from entering the fluidic path, while also being able to detect any malfunction or end of reservoir within few actuations, a long time ahead of existing pumps.
Unlike other insulin pumps, the JewelPUMP™ does not require such a substantial financial investment upfront as current pumps. Its design, with a permanent part containing the electronics and a disposable part containing the reservoir and the pumping mechanism, makes it affordable and attractive for every patient: patients who are already on a pump therapy and want to improve their quality of life, patients who want to start a pump therapy and patients who don't need a permanent supply of insulin (such as type II patients) but who would like to benefit from a pump therapy.
Image gallery of the MEMS Nanopump technology: